Most cases aren’t caused by “insulin resistance.” They are caused by diet—and that means they can be prevented or reversed.
Type 2 diabetes (T2D) is one of the fastest-growing health crises of our time.
Rising rapidly
Despite decades of research, treatment, and billions of dollars spent, the epidemic is accelerating.
👉 Something is missing in our understanding.
The dominant theory is insulin resistance: that muscle, fat, and liver cells stop responding to insulin. But this leaves major questions unanswered:
Out of 50+ hormones in the body, why would cells resist just this one?
Out of 200, why only muscle, liver, and fat cells?
If muscles resisted insulin, why do they still function normally?
If patients are “resistant,” why prescribe more insulin—and why do complications still develop?
👉 These contradictions show weaknesses in the insulin resistance model. Patients deserve better.
After 25 years of research, Dr. John Poothullil proposes a more consistent explanation: The Fatty Acid Burn Switch.
👉 This is not “resistance.” It’s a logical metabolic response to nutritional overload—consistent with the science of the Randle Cycle and clinical evidence.
The Fatty Acid Burn Switch reframes how we need to address Type 2 diabetes:
📌 Even the American Diabetes Association acknowledges that diet and exercise are more effective than insulin in preventing complications.
This is not just a scientific debate—it’s a public health crisis.
Millions are being told their bodies are “resistant to insulin” but that insulin is their only solution, even as complications continue.
This is illogical.
💡 The U.S. spends over $300 billion annually on type 2 diabetes care. Most of these costs could be reduced with prevention-first strategies rooted in nutrition science.
See how people have transformed their health with nutrition-first strategies
1. World Health Organization. Global action plan for the prevention and control of noncommunicable diseases 2013–2020. Geneva: WHO; 2013.
2. International Diabetes Federation. Diabetes Facts & Figures. Brussels: IDF; 2023.
3. Xie J, Wang M, et al. Global burden of type 2 diabetes in adolescents and young adults, 1990–2019. BMJ. 2022;379:e072385.
4. American Diabetes Association. Lifestyle Change Programs. Diabetes Care. 2022;45(Suppl 1):S101–S110.
5. Randle PJ, Newsome EA, Garland PB. Regulation of glucose uptake by muscle. Biochem J. 1964;93:652-665.
6. Poothullil J. Fullness of Fat Storage Capacity: An Alternative to Adipocyte Insulin Resistance. J Appl Res. 2001;1(1).
7. Petersen KF, et al. Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. Diabetes. 2005;54:603-608.
⚠️ This content is for educational purposes only and not medical advice. Always consult your doctor before making changes to your treatment or lifestyle.
© 2025 Dr. John Poothullil. All rights reserved.